Pomalidomide 4'-PEG4-acid incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. It is a synthesized E3 ligase ligand-linker conjugate[1].
References:
[1].Guangrong Zheng, et al. Compounds that induce degradation of anti-apoptotic bcl-2 family proteins and the uses thereof. WO2017184995A1.
Pomalidomide-PEG4-COOH 是一种 E3 连接酶配体-接头偶联物,包含基于 Pomalidomide 的 cereblon 配体和用于 PROTAC 技术的 4 单元 PEG 接头[1]。