Pentoxyverine Citrate (Carbetapentane) is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold.
Pentoxyverine (Carbetapentane) Citrate has atropine-like and local anaesthetic actions and effectively suppresses acute cough due to common upper respiratory infections. [1] Pentoxyverine suppresses the cough reflex in the central nervous system, but the exact mechanism of action is not known with certainty. The drug acts as an antagonist at muscarinic receptors (subtype M1) and as an agonist at sigma receptors (subtype σ1). Its anticholinergic properties can theoretically relax the pulmonary alveoli and reduce phlegm production. [2]
[1] D?nmez OA, et al. Talanta, 2011, 83(5), 1601-1605. [2] Brown C, et al. Br J Pharmacol, 2004, 141(2), 233-240.