Dodecanoyl D-Sucrose is a non-ionic type of biopersistent surfactant[1]. Dodecanoyl D-Sucrose was used as a surfactant to prepare stable nanoparticles, which enhanced the permeability of the model antigen protein ovocleidin-3[2]. Dodecanoyl D-Sucrose can be used as an absorption enhancer for percutaneous drug delivery, and is employed to prepare new hydrogels in order to enhance the bioavailability of estradiol in rabbits[3]. Dodecanoyl D-sucrose has been used to prepare stable foams in aqueous solutions, as well as oil-in-water emulsions[4].
References:
[1] Zhao L, Zhang H, Hao T, et al. In vitro antibacterial activities and mechanism of sugar fatty acid esters against five food-related bacteria[J]. Food chemistry, 2015, 187: 370-377.
[2] Kitaoka M, Imamura K, Hirakawa Y, et al. Sucrose laurate-enhanced transcutaneous immunization with a solid-in-oil nanodispersion[J]. MedChemComm, 2014, 5(1): 20-24.
[3] Vermeire A, De Muynck C, Vandenbossche G, et al. Sucrose laurate gels as a percutaneous delivery system for oestradiol in rabbits[J]. Journal of pharmacy and pharmacology, 1996, 48(5): 463-467.
[4] Zhang X, Wei W, Cao X, et al. Characterization of enzymatically prepared sugar medium‐chain fatty acid monoesters[J]. Journal of the Science of Food and Agriculture, 2015, 95(8): 1631-1637.
Dodecanoyl D-Sucrose是一种非离子型的生物持久性表面活性剂[1]。Dodecanoyl D-Sucrose被用作表面活性剂以制备稳定的纳米颗粒，从而增强模型抗原蛋白卵壳蛋白-3的渗透性[2]。Dodecanoyl D-Sucrose可作为经皮给药吸收促进剂，并用于制备新型水凝胶以提高雌二醇在兔体内的生物利用度[3]。此外，Dodecanoyl D-Sucrose可用于在水溶液中制备稳定的泡沫体系以及水包油型乳剂[4]。