Parvodicin C2 is a glycopeptide antibiotic originally isolated from A. parvosata and a component of parvodicin complex .1 It is also a component of the A40926 antibiotic complex, which has been used as a precursor in the synthesis of the antibiotic dalbavancin .2 Parvodicin C2 is active against methicillin-sensitive strains of S. aureus, S. epidermidis, and S. saprophyticus (MICs = 0.4-12.5 μg/ml), as well as methicillin-resistant strains of S. aureus, S. hemolyticus, and E. faecalis (MICs = 0.2-50 μg/ml).1
1.Christensen, S.B., Allaudeen, H.S., Burke, M.R., et al.Parvodicin, a novel glycopeptide from a new species, Actinomadura parvosata: Discovery, taxonomy, activity and structure elucidationJ. Antibiot. (Tokyo)40(7)970-990(1987) 2.Jovetic, S., Feroggio, M., Marinelli, F., et al.Factors influencing cell fatty acid composition and A40926 antibiotic complex production in Nonomuraea sp. ATCC 39727J. Ind. Microbiol. Biotechnol.35(10)1131-1138(2008)
















