GlpBio

N-Acetyl-L-thyroxine

目录号: GC49802纯度: >98.00%同义词: N-乙酰基L-甲状腺素
A thyroid hormone derivative
N-Acetyl-L-thyroxine
Cas No.: 26041-51-0
规格价格库存数量操作
100 mg¥2,047.00现货
1
250 mg¥4,600.00现货
1
500 mg¥7,170.00现货
1
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文献被引

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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

N-Acetyl-L-thyroxine is an acetylated derivative of L-thyroxine .1 It only weakly binds to thyroxine-binding globulin (TBG) in isolated human serum with a relative binding affinity of 25 compared with L-thyroxine. N-Acetyl-L-thyroxine is also a potential impurity in commercial preparations of L-thyroxine.2

1.Snyder, S.M., Cavalieri, R.R., Goldfine, I.D., et al.Binding of thyroid hormones and their analogues to thyroxine-binding globulin in human serumJ. Biol. Chem.251(21)6489-6494(1976) 2.Panmanad, D., Joshi, M.S., Patil, R., et al.Synthesis and characterization of potential impurities in levothyroxineChem. Sci. Trans.5(4)1082-1089(2016)

产品文档 Product Documents

Purity:>98.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
26041-51-0
同义词
N-乙酰基L-甲状腺素
SMILES
IC1=CC(C[C@@H](C(O)=O)NC(C)=O)=CC(I)=C1OC2=CC(I)=C(C(I)=C2)O
分子式
C17H13I4NO5
分子量
818.9 g/mol
溶解性
DMF: 14 mg/mL,DMSO: 25 mg/mL,Ethanol: 20 mg/mL,PBS (pH 7.2): 0.2 mg/mL
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol