Metronidazole benzoate is an antibiotic and antiprotozoal agent and ester form of metronidazole .1 It is active against P. asaccharolyticus, C. perfringens, C. septicum, B. fragilis, and B. thetaiotaomicron (MICs = 3.6, 7.3, 1.8, 7.3, and 7.3 ?M, respectively). Metronidazole reduces parasitemia in rats when cultured with T. congolense or T. b. gambiense prior to infection.2
1.Bowden, K., and Izadi, J.Prodrugs - Part 2. Acylbenzoate esters of metronidazoleEur. J. Med. Chem.32(12)995-1000(1998) 2.Ogunbanwo, J.A., Agbonlahor, D.E., Adamu, A., et al.Effects of anti-protozoal drugs and histopathological studies on trypanosome speciesFEMS Immunol. Med. Microbiol.30(1)73-83(2001)