GlpBio

Mca-YVADAP-K(Dnp)-OH (trifluoroacetate salt)

目录号: GC47607纯度: >95.00%同义词: Caspase-1 Fluorogenic Substrate V, Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH, Mca-YVADAP-Lys(Dnp)-OH, (7-Methoxycoumarin-4-yl)acetyl-YVADAPK(2,4-dinitrophenyl)-OH
A neuropeptide with diverse biological activities
Mca-YVADAP-K(Dnp)-OH (trifluoroacetate salt)
Cas No.: N/A
规格价格库存数量操作
500 μg¥2,433.00现货
1
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产品描述 Description

Mca-YVADAP-K(Dnp)-OH is a substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2).1,2 Upon cleavage by caspase-1 or ACE2, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify enzyme activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.

1.Vickers, C., Hales, P., Kaushik, V., et al.Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidaseJ. Biol. Chem.277(17)14838-14843(2002) 2.Enari, M., Talanian, R.V., Wong, W.W., et al.Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosisNature380(6576)723-726(1996)

产品文档 Product Documents

Purity:>95.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
N/A
同义词
Caspase-1 Fluorogenic Substrate V, Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH, Mca-YVADAP-Lys(Dnp)-OH, (7-Methoxycoumarin-4-yl)acetyl-YVADAPK(2,4-dinitrophenyl)-OH
SMILES
COC1=CC=C(C(CC(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N3CCC[C@H]3C(N[C@@H](CCCCNC4=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C4)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=CC(O5)=O)C5=C1.OC(C(F)(F)F)=O
分子式
C53H64N10O19.XCF3COOH
分子量
1145.1 g/mol
溶解性
Water: 1 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol