GlpBio

MBX-4132

目录号: GC19241纯度: >99.00%
MBX-4132，一种称为恶二唑的化学类别的成员，通过与细菌核糖体结合来抑制反式翻译。
MBX-4132
Cas No.: 2286411-30-9
规格价格库存数量操作
5mg¥675.00现货
1
10mg¥1,080.00现货
1
25mg¥2,250.00现货
1
50mg¥3,600.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

MBX-4132, a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome.

MBX-4132, which interferes with protein synthesis by blocking trans translation, has several characteristics that could make it a match for Neisseria gonorrhoeae (N. gonorrhoeae)[1].

References:
[1]. Anette Breindl, et al. Ribosome allows for multiple shots on giant goal.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
2286411-30-9
SMILES
O=C(NC1=NN=C(C2=CC=C(F)C=C2)O1)N3CCC4=CC=CC=C4C3
分子式
C18H15FN4O2
分子量
338.34 g/mol
溶解性
DMSO : 25 mg/mL (73.89 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol