GlpBio

I-191

目录号: GC64979纯度: >99.00%
I-191 is a potent PAR2 antagonist that inhibits multiple PAR2-induced signaling pathways and functional responses. I-191 also inhibits ERK1/2 phosphorylation, RhoA activation, and inhibition of forskolin-stimulated cAMP accumulation induced by micromolar concentrations of biased ligand GB88.
I-191
Cas No.: 1690172-25-8
规格价格库存数量操作
5mg¥3,150.00现货
1
10mg¥4,950.00现货
1
25mg¥9,900.00现货
1
50mg¥14,850.00现货
1
100mg¥23,850.00现货
1
10mM (in 1mL DMSO)¥3,465.00现货
1
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文献被引

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产品描述 Description

I-191 is a potent PAR2 antagonist that inhibits multiple PAR2-induced signaling pathways and functional responses. I-191 also inhibits ERK1/2 phosphorylation, RhoA activation, and inhibition of forskolin-stimulated cAMP accumulation induced by micromolar concentrations of biased ligand GB88.

[1] Yuhong Jiang , et al. J Pharmacol Exp Ther. 2018 Feb;364(2):246-257.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
1690172-25-8
分子式
C23H26FN5O2
分子量
423.48 g/mol
溶解性
DMSO : 8.33 mg/mL (19.67 mM; Need ultrasonic)|Water : < 0.1 mg/mL (insoluble)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol