GlpBio

Halofantrine hydrochloride (SKF-102886)

目录号: GC32377纯度: >98.00%同义词: 盐酸卤泛群,SKF-102886; WR-171669 hydrochloride
Halofantrine hydrochloride (SKF-102886)是一种具口服活性的抗疟药，能够有效对抗耐药性恶性疟原虫和间日疟原虫。
Halofantrine hydrochloride (SKF-102886)
Cas No.: 36167-63-2
规格价格库存数量操作
1mg¥792.00现货
1
5mg¥2,228.00现货
1
10mg¥3,762.00现货
1
10mM (in 1mL DMSO)¥2,633.00现货
1
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文献被引

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产品描述 Description

Halofantrine hydrochloride (SKF-102886) is an orally active antimalarial drug that is effective against drug-resistant Plasmodium falciparum and Plasmodium vivax[1]. Halofantrine hydrochloride (SKF-102886) can block delayed rectified potassium current by inhibiting the human Ether-a-go-go-related gene (HERG) channel.

References:
[1] Bryson H M, Goa K L. Halofantrine: a review of its antimalarial activity, pharmacokinetic properties and therapeutic potential[J]. Drugs, 1992, 43(2): 236-258.

Halofantrine hydrochloride (SKF-102886)是一种具口服活性的抗疟药，能够有效对抗耐药性恶性疟原虫和间日疟原虫[1]。Halofantrine hydrochloride (SKF-102886)能够通过抑制人Ether-a-go-go相关基因（HERG）通道来阻断延迟整流钾电流。

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
36167-63-2
同义词
盐酸卤泛群,SKF-102886; WR-171669 hydrochloride
SMILES
OC(CCN(CCCC)CCCC)C1=CC2=C(Cl)C=C(Cl)C=C2C3=CC(C(F)(F)F)=CC=C31.[H]Cl
分子式
C26H31Cl3F3NO
分子量
536.88 g/mol
溶解性
DMSO : 30 mg/mL (55.88 mM; Need ultrasonic)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol