GlpBio

H-Ile-Pro-Pro-OH hydrochloride

目录号: GC60190纯度: >98.00%
H-Ile-Pro-Pro-OH hydrochloride 是一种乳源三肽，抑制血管紧张素转换酶 (ACE) ，IC50 为 5 μM。具有抗高血压效果。
H-Ile-Pro-Pro-OH hydrochloride
Cas No.: 1208862-61-6
规格价格库存数量操作
50mg¥720.00现货
1
100mg¥990.00现货
1
250mg¥1,890.00现货
1
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产品描述 Description

H-Ile-Pro-Pro-OH hydrochloride, a milk-derived peptide[1], inhibits angiotensin-converting enzyme (ACE)[1] with an IC50 of 5 μM[2]. Antihypertensive tripeptides[1].

Ile-Pro-Pro (IPP; 1 nM, 0.1 μM, and 10 μM) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs)[1].

Ile-Pro-Pro (IPP; 30 mg/kg per day; 0.3 g/L) attenuates arterial dysfunction in L-NAME-treated rats[1]Ile-Pro-Pro decreases blood pressure in spontaneously hypertensive rats (SHR) [1].Ile-Pro-Pro attenuates the development of atherosclerosis in apolipoprotein E-deficient (apoE(-/-)) mice[1].

[1]. Nonaka A, et al. The milk-derived peptides Val-Pro-Pro and Ile-Pro-Pro attenuate arterial dysfunction in L-NAME-treated rats. Hypertens Res. 2014 Aug;37(8):703-7. [2]. Nakamura Y, et al. Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk. J Dairy Sci. 1995 Apr;78(4):777-83.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
1208862-61-6
分子式
C16H28ClN3O4
分子量
361.86 g/mol
溶解性
H<sub>2</sub>O : 55 mg/mL (151.99 mM; Need ultrasonic); DMSO : 36.67 mg/mL (101.34 mM; Need ultrasonic)
保存条件
-20&#176;C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol