GL0388

目录号: GC69163纯度: >98.00%
GL0388 是一种 Bax 激活剂,可导致 Bax 插入线粒体膜。GL0388 对多种癌细胞具有抗增殖活性,IC50 值为 0.299-1.57 μM。GL0388 激活 Bax 并诱导 Bax 介导的细胞凋亡。GL0388 在体内抑制乳腺癌异种移植肿瘤的生长。

GL0388
Cas No.: 2886772-68-3
规格价格库存数量操作
10mg¥3,780.00现货
1
25mg¥7,740.00现货
1
50mg¥12,780.00现货
1

文献被引

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产品描述 Description

GL0388 is a Significantly inhibited tumor growth at a dose of 15 mg/kg every other day.
I.T. administration for 10 consecutive days, with an inhibition rate of 55%, comparable to the I.P. efficacy at the dose of daily 20 mg/kg.

[1]. Liu G, et, al. Further lead optimization on Bax activators: Design, synthesis and pharmacological evaluation of 2-fluoro-fluorene derivatives for the treatment of breast cancer. Eur J Med Chem. 2021 Jul 5;219:113427.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
2886772-68-3
分子式
C21H17FN2O
分子量
332.37 g/mol
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol