3-hydroxy-9,10-Dimethoxypterocarpan is a flavonoid that has been found in A. membranaceus and has antiproliferative activity.1 It inhibits PDGF-BB-induced proliferation of, and DNA synthesis in, A-10 vascular smooth muscle cells (IC50s = 10 and 1 ?M, respectively).
1.Onhawara, S., Okuma, Y., Uehara, T., et al.Astrapterocarpan isolated from Astragalus membranaceus inhibits proliferation of vascular smooth muscle cellsEur. J. Pharmacol.525(1-3)41-47(2005)