GlpBio

Hydrocortisone buteprate

目录号: GC36267纯度: >99.50%同义词: 丙丁酸氢化可的松,Hydrocortisone probutate; HBP
Hydrocortisone buteprate (Hydrocortisone probutate) 是一种中等效力的非卤化氢化可的松双酯，对治疗炎症性皮肤疾病具有良好的利弊比。Hydrocortisone buteprate (Hydrocortisone probutate) 可作为 0.1% 乳膏或软膏配方提供。
Hydrocortisone buteprate
Cas No.: 72590-77-3
规格价格库存数量操作
10mg¥450.00现货
1
50mg¥1,350.00现货
1
100mg¥2,340.00现货
1
200mg¥0.01现货
1
500mg¥0.01现货
1
Free Sample (0.1-0.5 mg)¥0.01现货
1
10mM (in 1mL DMSO)¥495.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation[1].

[1]. FÖlster-Holst R, et al. Topical hydrocortisone 17-butyrate 21-propionate in the treatment of inflammatory skin diseases: pharmacological data, clinical efficacy, safety and calculation of the therapeutic index. Pharmazie. 2016 Mar;71(3):115-21.

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
72590-77-3
同义词
丙丁酸氢化可的松,Hydrocortisone probutate; HBP
SMILES
CCC(OCC([C@@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C(CC3)=CC(CC4)=O)C)([H])[C@@H](O)C2)([H])CC1)C)OC(CCC)=O)=O)=O
分子式
C28H40O7
分子量
488.61 g/mol
溶解性
DMSO: 250 mg/mL (511.66 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol