Coniferin is a phenylpropanoid glycoside and a lignan precursor that has been found in V. album and has diverse biological activities.1,2,3 It inhibits ADP-induced platelet aggregation in isolated human platelet-rich plasma when used at concentrations ranging from 0.01 to 1 ?M.1 Coniferin has antioxidant activity in an oxygen radical absorbance capacity (ORAC) assay.2 It induces contractions in isolated rat aortic rings when used at concentrations ranging from 0.001 to 1 mM.3 In vivo, coniferin (1 mg/kg) increases blood pressure in spontaneously hypertensive rats.4
1.Panossian, A., Kocharian, A., Matinian, K., et al.Pharmacological activity of phenylpropanoids of the mistletoe, Viscum album L., host: Pyrus caucasica Fed.Phytomedicine5(1)11-17(1998) 2.Kayano, S., Kikuzaki, H., Ikami, T., et al.A new bipyrrole and some phenolic constituents in prunes (Prunus domestica L.) and their oxygen radical absorbance capacity (ORAC)Biosci. Biotechnol. Biochem.68(4)942-944(2004) 3.Deliorman, D., ?ali?, ?., Ergun, F., et al.Studies on the vascular effects of the fractions and phenolic compounds isolated from Viscum album ssp. albumJ. Ethnopharmacol.72(1-2)323-329(2000) 4.Sawabe, A., Kumamoto, H., and Matsubara, Y.Bioactive glycosides in citrus fruit peelsBull. Inst. Compr. Agr. Sci. Kinki Univ.657-67(1998)