GlpBio

Aristolactam I

目录号: GC35388纯度: >99.50%同义词: 马兜铃内酰胺,Aristololactam; Aristolactam
Aristololactam I (AL-I) 是马兜铃酸I (AA-I) 的主要代谢产物，参与导致肾损伤的过程。Aristololactam I (AL-I) 直接损伤肾近端小管细胞，AL-I 的细胞毒性效力高于AA-I，并且这些分子的细胞毒性作用是通过 caspase-3 依赖性细胞凋亡介导。
Aristolactam I
Cas No.: 13395-02-3
规格价格库存数量操作
1mg¥540.00现货
1
5mg¥1,260.00现货
1
10mg¥2,160.00现货
1
10mM (in 1mL DMSO)¥1,742.00现货
1
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文献被引

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产品描述 Description

Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage.Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway[1].

[1]. Li J, et al. Toxicities of aristolochic acid I and aristololactam I in cultured renal epithelial cells. Toxicol In Vitro. 2010 Jun;24(4):1092-7.

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
13395-02-3
同义词
马兜铃内酰胺,Aristololactam; Aristolactam
SMILES
O=C1NC2=C(C3=C4C(C(OC)=CC=C4)=C2)C1=CC5=C3OCO5
分子式
C17H11NO4
分子量
293.27 g/mol
溶解性
DMSO : 12.5 mg/mL (42.62 mM; Need ultrasonic); H<sub>2</sub>O : &lt; 0.1 mg/mL (insoluble)
保存条件
4&#176;C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol