Fumagillin

目录号: GC12358纯度: >95.00%同义词: 烟曲霉素; Amebacilin; NSC9168
A fungal metabolite with diverse biological activities

Fumagillin
Cas No.: 23110-15-8
规格价格库存数量操作
1mg¥624.00现货
1
5mg¥2,174.00现货
1
10mg¥3,875.00现货
1
25mg¥6,120.00现货
1

文献被引

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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Fumagillin(NSC9168) is a complex biomolecule and used as an antimicrobial agent.Target: AntiparasiticFumagillin is an active amebicide and anti-infective isolated from the fungus Aspergillus fumigatus. Fumagillin does exhibit some side effects that have deterred its acceptance as a viable treatment, but the current body of research on the synthesis of novel analogs of this molecule shows an exciting and promising revival of this drug as both an anti-infective and antiangiogenic agent [1].

References:
[1]. Lefkove, B., B. Govindarajan, and J.L. Arbiser, Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors. Expert Rev Anti Infect Ther, 2007. 5(4): p. 573-9.

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
23110-15-8
同义词
烟曲霉素; Amebacilin; NSC9168
化学名
10-[[5-methoxy-4-[2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy]-10-oxodeca-2,4,6,8-tetraenoic acid
SMILES
CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C
分子式
C26H34O7
分子量
458.55 g/mol
溶解性
≥ 81.3mg/mL in DMSO, ≥ 2.58 mg/mL in EtOH with ultrasonic
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol