Flunisolide is a fluorinated corticosteroid receptor agonist that induces reversible pyloric hyalinization in CD-1 mice following oral administration at a dose of 200 μg/kg per day.1 Formulations containing flunisolide have been used for the treatment of asthma.2
1.McKevitt, T.P., Giffen, P., Woodfine, J.A., et al.Hyalinization of the pyloric stomach in CD-1 mice following oral (dietary) administration of the corticosteroid agonists mometasone furoate, budesonide, and flunisolideToxicol. Pathol.39(6)958-968(2011) 2.O'Callaghan, C., White, J.A., and Kantar, A.Nebulization of corticosteroids to asthmatic children: Large variation in dose inhaledRespirology19(2)276-279(2014)