Farnesyl-Diphosphate Farnesyltransferase 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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FDFT1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 306 amino acids (1-283 a.a) andhaving a molecular mass of 35.4 kDa.FDFT1 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Farnesyl-Diphosphate Farnesyltransferase 1; SqualeneSynthase; SQS; SS; FPP:FPP Farnesyltransferase; EC 2.5.1.21; DGPT; ERG9; Presqualene-Di-DiphosphateSynthase; Squalene Synthetase; Farnesyl-Diphosphate; Farnesyltransferase; FDFT1. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMEFVKCL GHPEEFYNLV RFRIGGKRKV MPKMDQDSLS SSLKTCYKYLNQTSRSFAAV IQALDGEMRN AVCIFYLVLR ALDTLEDDMT ISVEKKVPLL HNFHSFLYQP DWRFMESKEKDRQVLEDFPT ISLEFRNLAE KYQTVIADIC RRMGIGMAEFLDKHVTSEQE WDKYCHYVAGLVGIGLSRLF SASEFEDPLV GEDTERANSM GLFLQKTNII RDYLEDQQGG REFWPQEVWS RYVKKLGDFA KPENIDLAVQCLNELITNAL HHIPDVITYL SRLRNQ. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | FDFT1 protein solution (0.25 mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea. | ||
Farnesyl-Diphosphate Farnesyltransferase 1, also known as FDFT1 is amembrane-associated enzyme sited at a branch point in the mevalonate pathway. FDFT1belongs to the phytoene/squalene synthase family. FDFT1 is the 1st specificenzyme in cholesterol biosynthesis, which catalyzes the dimerization of 2molecules of farnesyl diphosphate in a two-step reaction to form squalene.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.