Enniatins are cyclohexadepsipeptides commonly isolated from fungi that are known to have antibiotic properties and to induce apoptosis in several cancer lines. Many function as ionophores, forming pores in cellular membranes to allow selective ion transport. Enniatin A1 is one of four major analogs in the enniatin complex . Its ionophoric activity has been described. Additionally, enniatin A1 has been found to induce apoptosis in cancer cells (EC50 = 5 µM in H4IIE rat hepatoma cells), decreasing the activation of the cell proliferation kinase, ERK (p44/p42) and inhibiting TNF-α-induced NF-κB activation.
Enniatin A1
目录号: GC43610纯度: >99.00%同义词: 恩镰孢菌素 A1
An ionophore antibiotic
Cas No.: 4530-21-6
| 规格 | 价格 | 库存 | 数量 | 操作 |
|---|---|---|---|---|
| 1mg | ¥2,556.00 | 现货 | 1 | |
| 5mg | ¥10,749.00 | 现货 | 1 |
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Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
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产品描述 Description
产品文档 Product Documents
Purity:>99.00%Appearance:A Powder
化学性质Chemical Properties
CAS 号
4530-21-6
同义词
恩镰孢菌素 A1
SMILES
C[C@@H](CC)[C@]([H])(N(C)C([C@@H](C(C)C)OC([C@H]([C@H](CC)C)N(C)C1=O)=O)=O)C(O[C@]([H])(C(C)C)C(N(C)[C@@H](C(C)C)C(O[C@@H]1C(C)C)=O)=O)=O
分子式
C35H61N3O9
分子量
667.9 g/mol
溶解性
DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。
计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度
g/mol