DMNPE-4 AM-caged-calcium

目录号: GC50302纯度: >90.00%
DMNPE-4 AM-caged-calcium 是 EGTA 的光不稳定类似物,是一种非常有效的 Ca2+ 选择性笼,在 pH 7.2 和 pH 7.4 下,Ca2+ 的 Kd 分别为 48 nM 和 19 nM。

DMNPE-4 AM-caged-calcium
Cas No.: 2253744-58-8
规格价格库存数量操作
5 mg¥6,350.00现货
1

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产品描述 Description

Caged calcium (Kd values are 48 and 19 nM at pH 7.2 and 7.4, respectively; Kd after uncaging = 2 mM). Selective over Mg2+ (Kd =10 mM). Rapid and efficient calcium release upon photolysis at 350 nm. Can also be used for two-photon uncaging. Extinction coefficient of 5120 M-1 cm-1, quantum yield 0.09. Cell permeable.

Wang et al (2015) Spontaneous activity of cochlear hair cells triggered by fluid secretion mechanism in adjacent support cells Cell 163 1348 PMID:26627734 |Gordon et al (2008) Brain metabolism dictates the polarity of astrocyte control over arterioles. Nature 456 745 PMID:18971930 |Ellis-Davies et al (2006) Tuning caged calcium: photolabile analogues of EGTA with improved optical and chelation properties. Cell Calcium 39 75 PMID:16303177

产品文档 Product Documents

Purity:>90.00%

化学性质Chemical Properties

CAS 号
2253744-58-8
SMILES
O=C(OCOC(C)=O)CN(CC(OCOC(C)=O)=O)CCOCCOC(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(C=C1OC)=C(C=C1OC)[N+]([O-])=O
分子式
C34H47N3O22
分子量
849.74 g/mol
溶解性
Soluble in DMSO
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol