Didrobaicalein is a PLK1 Inhibitor with an IC50 of 6.3 μM. Didrobaicalein also inhibits VRK2 and PLK2. Didrobaicalein is a natural product that can be isolated from Scutellaria scandens.
References:
[1]. Woo SU, et al. 7-O-Metlwogonin from Scutellaria baicalensis Disturbs Mitotic Progression by Inhibiting Plk1 Activity in Hep3B Cells. Planta Med. 2019 Feb;85(3):217-224.
















