GlpBio

Desmethyl-VS-5584 hydrochloride

目录号: GC72768纯度: >98.00%同义词: Desmethyl-SB2343 hydrochloride
Desmethyl-VS-5584 hydrochloride是VS-5584的二甲基类似物，VS-5584是一种有效的选择性双mTOR/PI3K抑制剂，具有吡啶[2,3-d]嘧啶结构。
Desmethyl-VS-5584 hydrochloride
规格价格库存数量操作
1 mg¥796.00现货
1
5 mg¥1,584.00现货
1
10 mg¥2,534.00现货
1
25 mg¥4,928.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Desmetl-VS-5584 drochloride is a dimetl analog of VS-5584, a potent and selective mTOR/PI3KDual inhibitor, with a pyridine[2,3-d]pyrimidine structure.

References:
[1]. Hart S, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013;12(2):151-161.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

同义词
Desmethyl-SB2343 hydrochloride
分子式
C16H22Cl2N8O
分子量
413.3 g/mol
溶解性
DMSO : 2.67 mg/mL (6.46 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)
保存条件
4°C, sealed storage, away from moisture
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol