GlpBio

(+)-Corynoline

目录号: GN10654纯度: >98.00%同义词: 紫蓳灵
An isoquinoline alkaloid with diverse biological activities
(+)-Corynoline
Cas No.: 18797-79-0
规格价格库存数量操作
5mg¥540.00现货
1
10mg¥900.00现货
1
20mg¥1,620.00现货
1
10mM (in 1mL DMSO)¥594.00现货
1
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文献被引

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产品描述 Description

Corynoline, isolated from Corydalis incise (Papaveraceae), is a reversible and noncompetitive acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM[1]. Corynoline exhibits anti-inflammatory activity by activating Nrf2[2].

References:
[1]. Kim DK. Inhibitory effect of corynoline isolated from the aerial parts of Corydalis incisa on the acetylcholinesterase. Arch Pharm Res. 2002 Dec;25(6):817-9.
[2]. Liu B, et al. Corynoline Exhibits Anti-inflammatory Effects in Lipopolysaccharide (LPS)-Stimulated Human Umbilical Vein Endothelial Cells through Activating Nrf2. Inflammation. 2018 Oct;41(5):1640-1647.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
18797-79-0
同义词
紫蓳灵
化学名
5b,13-dimethyl-5b,6,7,12b,13,14-hexahydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-6-ol
SMILES
[H]C1(C2=C([H])C3=C4OC([H])([H])O3)N(C([H])([H])[H])C([H])([H])C5=C(C([H])=C([H])C6=C5OC([H])([H])O6)C1(C([H])([H])[H])C(C([H])([H])C2=C4[H])([H])O[H]
分子式
C21H21NO5
分子量
367.14 g/mol
溶解性
Chloroform: 10 mg/ml,DMF: slightly soluble,Ethanol: slightly soluble
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol