Cintirorgon is a retinoic acid receptor-related orphan receptor ? (ROR?) agonist with EC50 values of less than 0.5 ?M in a reporter assay and time-resolved FRET (TR-FRET) assay.1
1.Aicher, T.D., Taylor, C.B., and Vanhuis, C.A.Aryl dihydro-2h-benzo[b][1,4]oxazine sulfonamide and related compounds for use as agonists of RORy and the treatment of disease(2016)
















