GlpBio

C10 Ceramide (d18:1/10:0)

目录号: GC43004纯度: >98.00%同义词: N-癸酰-D-鞘胺醇,N-decanoyl-D-erythro-Sphingosine
A bioactive sphingolipid
C10 Ceramide (d18:1/10:0)
Cas No.: 111122-57-7
规格价格库存数量操作
5mg¥1,181.00现货
1
10mg¥2,244.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase. [1] C10 ceramide inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells with IC50 values of 44.1 and 46 μM, respectively. It also inhibits the growth of J774 murine macrophages in a dose-dependent manner.

Reference:
[1]. Shabbits, J.A., and Mayer, L.D. Intracellular delivery of ceramide lipids via liposomes enhances apoptosis in vitro. Biochim Biophys. Acta. 1612(1), 98-106 (2003).

产品文档 Product Documents

Purity:>98.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
111122-57-7
同义词
N-癸酰-D-鞘胺醇,N-decanoyl-D-erythro-Sphingosine
化学名
N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-decanamide
SMILES
OC[C@H](NC(CCCCCCCCC)=O)[C@H](O)/C=C/CCCCCCCCCCCCC
分子式
C28H55NO3
分子量
453.7 g/mol
溶解性
20mg/mL in DMSO, 22mg/mL in DMF, 33mg/mL in Ethanol
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol