GlpBio

Biotin-PEG4-amino-t-Bu-DADPS-C6-azide

目录号: GC60646纯度: >95.00%同义词: DADPS叠氮生物素
Biotin-PEG4-amino-t-Bu-DADPS-C6-azide是一种PROTAClinker，属于PEG类。可用于合成PROTAC分子。
Biotin-PEG4-amino-t-Bu-DADPS-C6-azide
Cas No.: 1260247-50-4
规格价格库存数量操作
5mg¥2,268.00现货
1
10mg¥3,407.00现货
1
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文献被引

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产品描述 Description

Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
1260247-50-4
同义词
DADPS叠氮生物素
SMILES
O=C(NCC(C)(O[Si](C1=CC=CC=C1)(OCCCCCCN=[N+]=[N-])C2=CC=CC=C2)C)CCOCCOCCOCCOCCNC(CCCC[C@@H]3SC[C@]([C@]3([H])N4)([H])NC4=O)=O
分子式
C43H67N7O9SSi
分子量
886.18 g/mol
溶解性
DMSO: 100 mg/mL (112.84 mM)
保存条件
-20°C, protect from light,unstable in solution, ready to use.
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol