| 规格 | 价格 | 库存 | 数量 | 操作 |
|---|---|---|---|---|
| 25mg | ¥687.00 | 现货 | 1 | |
| 50mg | ¥1,071.00 | 现货 | 1 | |
| 100mg | ¥1,517.00 | 现货 | 1 | |
| 10mM (in 1mL DMSO) | ¥756.00 | 现货 | 1 |
Beclomethasone is a glucocorticoid.1 It reduces plasma corticosteroid levels in rats when administered at doses ranging from 1 to 10 mg/kg.
1.Yamamoto, S.Glucocorticoid action of beclomethasone and its propionate ester derivativesNihon Yakurigaku Zasshi73(1)25-36(1976)
Cell experiment: | The transgenic lines Tg(fli1:GFP) and Tg(mpx:GFP) are used in this study. 0.2 mM N-phenylthiourea (PTU) is applied to prevent pigment formation from 1 day post-fertilization (dpf). For Pu.1 knockdown, Pu.1 MO (1 mM for partial knockdown and 2 mM for complete knockdown is injected into the yolk at the one-cell stage. For pharmacological inhibition, the VEGFR tyrosine kinase inhibitors KRN633 (0.1-1 μM) or Sunitinib (0.1-1 μM), Beclomethasone (25 μM) and β-amino-proprionitrile (βAPN, 500 μM) are applied directly to the egg water and refreshed every 2 days. For pharmacological inhibition, Beclomethasone is applied to the embryos 4 h before implantation and KRN633, Sunitinib and βAPN are applied 4-6 h post-implantation. For each cell line or condition, data are representative of ≥ three independent experiments, with ≥30 embryos/group. Experiments are discarded when the survival rate of the control group is <90%[1]. |
References: [1]. He S, et al. Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. J Pathol. 2012 Aug;227(4):431-45. |
