GlpBio

AZD-0284

目录号: GC31880纯度: >99.50%
AZD-0284是核受体RORγ的反向激动剂。在开发用于治疗寻常型斑块状银屑病和呼吸道疾病。
AZD-0284
Cas No.: 2101291-07-8
规格价格库存数量操作
1mg¥594.00现货
1
5mg¥1,512.00现货
1
10mg¥2,268.00现货
1
25mg¥3,510.00现货
1
50mg¥5,076.00现货
1
10mM (in 1mL DMSO)¥1,744.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].

[1]. Narjes, F, et al. The discovery of AZD0284, an inverse agonist of the nuclear receptor RORg. American Chemical Society, 2017 Drug Design and Delivery Symposium 26 October 2017

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
2101291-07-8
SMILES
O=C([C@@H]1N(C(C)=O)CC2=C1C=CC(S(=O)(C)=O)=C2)NC3=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C3
分子式
C21H18F6N2O5S
分子量
524.43 g/mol
溶解性
DMSO : 100 mg/mL (190.68 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol