Alloepipregnanolone

目录号: GC33807纯度: >98.00%同义词: 别孕烯醇酮

An Analytical Reference Standard

Cas No.: 516-55-2

规格	价格	库存	数量	操作
100mg	¥536.00	现货	1

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产品描述 Description

5α-Pregnan-3β-ol-20-one is an analytical reference standard categorized as a steroid metabolite.¹ 5α-Pregnan-3β-ol-20-one is a metabolite of progesterone. 5α-Pregnan-3β-ol-20-one is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

1.Murphy, B.E.P., Abbott, F.V., Allison, C.M., et al.Elevated levels of some neuroactive progesterone metabolites, particularly isopregnanolone, in women with chronic fatigue syndromePsychoneuroendocrinology29(2)245-268(2004)

实验参考方法 Experimental Reference Method

Animal experiment:

Mice[1]Male Swiss mice are pretreated with Alloepipregnanolone (isopregnanolone: 0.05, 0.10 or 0.20 mg/kg) 30 min before administration of ethanol (1.5 g/kg). Twenty-four hours later, all animals tested using the plus-maze apparatus. The first experiment defines the doses of ethanol that does or does not induce rapid tolerance to the anxiolytic effect of ethanol. In the second, the influence of pretreatment of mice with Alloepipregnanolone (0.05, 0.10 or 0.20 mg/kg) on rapid tolerance to ethanol (1.5 g/kg) is studied[1].

References:

[1]. Debatin T, et al. Effect of isopregnanolone on rapid tolerance to the anxiolytic effect of ethanol. Rev Bras Psiquiatr. 2006 Mar;28(1):18-23.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号

516-55-2

同义词

别孕烯醇酮

SMILES

CC([C@H]1CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O

分子式

C₂₁H₃₄O₂

分子量

318.49 g/mol

溶解性

Ethanol: 10 mg/mL (31.40 mM); DMSO: 3.33 mg/mL (10.46 mM)

保存条件

Store at -20°C

General tips

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。

Shipping Condition

评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

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分子量 (MW)

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