Aldosterone is a steroid hormone secreted by the adrenal cortex and is the principle mineralocorticoid controlling sodium and potassium balance.[1],[2] Its primary role is to promote unidirectional salt reabsorption in epithelial tissues. Aldosterone is synthesized from cholesterol in the zona glomerulosa of the adrenal cortex and its secretion is regulated via the renin-angiotensin system.[3]
醛固酮是由肾上腺皮质分泌的一种类固醇激素，是控制钠和钾平衡的主要矿物质皮质激素。它的主要作用是促进上皮组织中单向盐吸收。醛固酮从胆固醇合成于肾上腺皮层的球状带，并通过肾素-血管紧张素系统调节其分泌。
Reference:
[1]. Agarwal, M.K., and Mirshahi, M. General overview of mineralocorticoid hormone action. Pharmacology & Toxicology 84, 273-326 (1999).
[2]. Rogerson, F.M., and Fuller, P.J. Mineralocorticoid action. Steroids 65, 61-73 (2000).
[3]. Lumbers, E.R. Angiotensin and aldosterone. Regulatory Peptides 80, 91-100 (1999).