GlpBio

3'3'-cGAMP (sodium salt)

目录号: GC42245纯度: >98%同义词: AdenosineGuanosine 3',3'-cyclic monophosphate, 3',3'-Cyclic GMP-AMP, c-GpAp
COASDSData Sheet
A second messenger and inducer of IFN-β production
3'3'-cGAMP (sodium salt)
Cas No.: 2407516-83-8
规格价格库存数量操作
100μg¥820.00现货
1
500μg¥1,710.00现货
1
1mg¥2,970.00现货
1
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文献被引

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    641, 529–536 (2025)
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    183(7):1867-1883 (2020)
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产品描述 Description

3'3'-cGAMP is a second messenger produced in bacteria by specific dinucleotide cyclases. It contains canonical 3'5'-phosphodiester bonds and regulates chemotaxis, colonization, and other cellular functions. 3'3'-cGAMP shows weaker binding to the adapter protein stimulator of interferon genes (STING; Kd = 1.04 µM) than 2'2'-cGAMP and 2'3'-cGAMP but has similar binding affinity to 3'2'-cGAMP (Kd = 1.61 µM) and cyclic di-GMP . 3'3'-cGAMP induces IFN-β mRNA expression in L929 cells (EC50 = 40.5 nM).

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
2407516-83-8
同义词
AdenosineGuanosine 3',3'-cyclic monophosphate, 3',3'-Cyclic GMP-AMP, c-GpAp
SMILES
O=C1NC(N)=NC2=C1N=CN2[C@@H]([C@@H]3O)O[C@@]([H])([C@]3(OP([O-])(OC[C@]([H])([C@]4(O5)[H])O[C@H]([C@@H]4O)N6C7=NC=NC(N)=C7N=C6)=O)[H])COP5([O-])=O.[Na+].[Na+]
分子式
C20H22N10O13P2•2Na
分子量
718.4 g/mol
溶解性
Water: 10 mM
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol