GlpBio

2-Iminobiotin hydrobromide

目录号: GC39326纯度: >98.00%同义词: 2-亚氨基生物素盐酸盐; Guanidinobiotin hydrobromide
2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) 是一种生物素 (维生素 H 或 B7) 类似物。2-Iminobiotin hydrobromide 是一种可逆的 NO 合酶抑制剂，作用于小鼠 iNOS 和大鼠 n-cNOS，Ki 值分别为 21.8 和 37.5 μM。2-Iminobiotin hydrobromide 与低温环境可保护人类神经细胞免受缺氧诱导的细胞损伤。
2-Iminobiotin hydrobromide
Cas No.: 76985-52-9
规格价格库存数量操作
10mg¥1,350.00现货
1
50mg¥4,050.00现货
1
10mM (in 1mL DMSO)¥1,485.00现货
1
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产品描述 Description

2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS, respectively[1]. 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage[2].

[1]. Sup SJ, et al. 2-Iminobiotin is an inhibitor of nitric oxide synthases. Biochem Biophys Res Commun. 1994 Oct 28;204(2):962-8. [2]. Zitta K, et al. 2-Iminobiotin Superimposed on Hypothermia Protects Human Neuronal Cells from Hypoxia-Induced Cell Damage: An in Vitro Study. Front Pharmacol. 2018 Jan 11;8:971.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
76985-52-9
同义词
2-亚氨基生物素盐酸盐; Guanidinobiotin hydrobromide
SMILES
[H][C@](CS[C@H]1CCCCC(O)=O)([C@]1([H])N2)NC2=N.Br
分子式
C10H18BrN3O2S
分子量
324.24 g/mol
溶解性
DMSO: 125 mg/mL (385.52 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol