1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC is an oxidized phospholipid that contains palmitic acid and 13(S)-HODE at the sn-1 and sn-2 positions, respectively. It has been used to detect the activity of glutathione peroxidase 4 (GPX4), also known as phospholipid hydroperoxide glutathione peroxidase (PhGPx), using 1-palmitoyl-2-13(S)-HpODE-sn-glycero-3-PC as the substrate.1
References:
[1]. Bao, Y., Chambers, S.J., and Williamson, G.Direct separation of hydroperoxy- and hydroxy-phosphatidylcholine derivatives: Application to the assay of phospholipid hydroperoxide glutathione peroxidaseAnal. Biochem.224(1)395-399(1995).
















