Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases.
References:
[1]. Cong Y, et al. Steroidal Alkaloids from Veratrum maackii Regel with Genotoxicity on Brain-Cell DNA in Mice. Helv Chim Acta. 2015, 98(4): 539-545.
[2]. Augustin MM, et al. Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. Plant J. 2015 Jun;82(6):991-1003.