GlpBio

U-74389G

目录号: GC45108纯度: >99.00%同义词: Methylated Tirilazad
An antioxidant that prevents iron-dependent lipid peroxidation
U-74389G
Cas No.: 153190-29-5
规格价格库存数量操作
50mg¥1,109.00现货
1
100mg¥1,771.00现货
1
250mg¥4,096.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.[1],[2],[3],[4]

Reference:
[1]. Ishizaki, N., Zhu, Y., Zhang, S., et al. Comparison of various lazaroid compounds for protection against ischemic liver injury. Transplantation 63, 202-208 (1997).
[2]. Palma-Vargas, J.M., Toledo, A.H., García-Criado, F.J., et al. 21-Aminosteroids block neutrophil infiltration and provide liver protection independent of nitrite/nitrate levels. Journal of Surgical Research 66, 131-137 (1996).
[3]. Perna, A.M., Liguori, P., Bonacchi, M., et al. Protection of rat heart from ischaemia-reperfusion injury by the 21-aminosteroid U-74389G. Pharmacological Research 34, 25-31 (1996).
[4]. Shoskes, D.A., Xie, Y., and Gonzalez-Cadavid, N.F. Nitric oxide synthase activity in renal ischemia-reperfusion injury in the rat. Implications for renal transplantation. Transplantation 63, 495-500 (1997).

产品文档 Product Documents

Purity:>99.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
153190-29-5
同义词
Methylated Tirilazad
化学名
21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]-pregna-1,4,9(11)-triene-3,20-dione maleate salt
SMILES
C[C@@]12[C@](CC[C@@H]2C(CN3CCN(C4=CC(N5CCCC5)=NC(N6CCCC6)=N4)CC3)=O)([H])[C@](C7=CC1)([H])CCC([C@]7(C)C=C8)=CC8=O.OC(/C=C\C(O)=O)=O
分子式
C37H50N6O2•C4H4O4
分子量
726.9 g/mol
溶解性
1mg/mL in ethanol, 35mg/mL in DMSO, 36mg/mL in DMF
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol