GlpBio

Triptonide

目录号: GC14037纯度: >99.50%同义词: 雷公藤内酯酮; NSC 165677; PG 492
A diterpenoid with diverse biological activities
Triptonide
Cas No.: 38647-11-9
规格价格库存数量操作
10mg¥1,523.00现货
1
10mM (in 1mL DMSO)¥903.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Triptonide(NSC 165677; PG 492), extracted from Tripterygium wilfordii Hook, inhibited the proliferation of mouse splenocytes induced by suboptimal concentration of concanavalin A or lipopolysaccharide at concentrations of 0.02, 0.1, and 0.5 mg/ml.

References:
[1]. Wu YW, Jiang YY, Xiao TX, Zhang HL.Determination of triptonide by cloud point extraction combined with MEKC.J Sep Sci. 2008 Mar;31(5):865-71.
[2]. Yao J, Zhang L, Zhao X, Hu L, Jiang Z.Simultaneous determination of triptolide, wilforlide A and triptonide in human plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry.Biol Pharm Bull. 2006 Jul;29(7):1483-6.
[3]. Wang Z, Wen J, Xing J, Guo D.Determination of triptolide and triptonide in human plasma by high-performance liquid chromatography.Biomed Chromatogr. 2005 Jan;19(1):60-2.
[4]. Wang L, Ye W, Hui L, Liu X, Guo Y.[Male contraception of triptonide and its function mechanism].Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2000 Jun;22(3):223-6.
[5]. Corson, Timothy W.; Cavga, Hueseyin; Aberle, Nicholas; Crews, Craig M. Triptolide Directly Inhibits dCTP Pyrophosphatase. ChemBioChem (2011), 12(11), 1767-1773.

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
38647-11-9
同义词
雷公藤内酯酮; NSC 165677; PG 492
化学名
(5bS,6aS,7aS,8aS,9aS,9bS,10aS,10bS)-8a-isopropyl-10b-methyl-1,5b,6,6a,8a,9a,9b,10b-octahydrotris(oxireno)[2',3':4b,5;2'',3'':6,7;2''',3''':8a,9]phenanthro[1,2-c]furan-3,8(2H,5H)-dione
SMILES
CC([C@]12[C@](O2)([H])[C@@](O3)([H])[C@@]43[C@]5(CCC6=C([C@]5([H])C[C@@](O7)([H])[C@@]47C1=O)COC6=O)C)C
分子式
C20H22O6
分子量
358.39 g/mol
溶解性
≥ 16.35 mg/mL in DMSO
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol