Terminolic acid

目录号: GC61321纯度: >98.00%同义词: 积雪草苷B苷元
Terminolicacid是一种从Combretumracemosum中分离出的五环三萜糖苷。Terminolicacid可以通过结合IL-1β和IL-6的受体活性位点来抑制促炎细胞因子,并且可以通过结合IL4受体的结合位点来增强抗炎细胞因子。Terminolicacid还表现出中等的抗菌活性。

Terminolic acid
Cas No.: 564-13-6
规格价格库存数量操作
1mg¥315.00现货
1
5mg¥855.00现货
1
10mg¥1,350.00现货
1

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产品描述 Description

Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum. Terminolic acid can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites. Terminolic acid also exhibits moderate antibacterial activity[1][1].

[1]. Gossan DPA, et, al. Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum. Fitoterapia. 2016 Apr;110:89-95. [2]. Legiawati L, et, al. In silico study of Centella asiatica active compounds as anti-inflammatory agent by decreasing Il-1 and Il-6 activity, promoting Il-4 activity. /J. Pharm. Sci. & Res. Vol. 10(9), 2018, 2142-2147.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
564-13-6
同义词
积雪草苷B苷元
SMILES
C[C@@]1(C[C@H]2O)[C@@](CC=C([C@]3([H])CC4(C)C)[C@]1(CC[C@]3(CC4)C(O)=O)C)([H])[C@]([C@]2([H])[C@@](C)([C@H]5O)CO)(C[C@H]5O)C
分子式
C30H48O6
分子量
504.7 g/mol
溶解性
DMSO : 100 mg/mL (198.14 mM; ultrasonic and warming and heat to 60°C)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol