Stearic acid-d3 is a deuterium-labeled stearic acid, serving as a stable isotope-labeled derivative of stearic acid. Stearic acid-d3 can be used as a tracer to trace the metabolic processes of stearic acid in biological systems, and also serves as an internal standard in NMR, GC-MS, or LC-MS analyses for quantitative analysis[1-3].
References:
[1] Shen MC, Zhao X, Siegal GP, et al. Dietary stearic acid leads to a reduction of visceral adipose tissue in athymic nude mice. PLoS One. 2014 Sep 15;9(9):e104083.
[2] Russak EM, Bednarczyk EM. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[3] Dumont A, de Rosny C, Kieu TL, et al. Docosahexaenoic acid inhibits both NLRP3 inflammasome assembly and JNK-mediated mature IL-1β secretion in 5-fluorouracil-treated MDSC: implication in cancer treatment. Cell Death Dis. 2019 Jun 19;10(7):485.
Stearic acid-d3是一种氘标记的硬脂酸，是硬脂酸的稳定同位素标记衍生物。Stearic acid-d3可作为示踪剂追踪硬脂酸在生物体内的代谢过程，同时可作为NMR、GC-MS或LC-MS分析中的内标品用于定量分析[1-3]。