关于 "Topoisomerase" 的结果79+ 个结果
- DichlorogelignateCAS: 164030-91-5
Dichlorogelignate (compound 4) is a selective inhibitor oftopoisomeraseII (Topo II). Dichlorogelignate has 100% inhibition at 50 μM.
- erythro-Austrobailignan-6CAS: 114127-24-1
erythro-Austrobailignan-6 is an orally active anti-cancer agent. erythro-Austrobailignan-6 inhibits DNAtopoisomeraseI and II activity. erythro-Austrobailignan-6 induces cellapoptosisand increases phosphorylation of p38 andJNK.
- Val-Ala-PAB-SN38 TFA
Val-Ala-PAB-SN38 TFA 是一种 ADC 的药物-连接子偶联物 (drug-linker conjugate for ADC)，由ADC linkerVal-Ala-PAB 和 SN38 组成，SN-38是拓扑异构酶 I (TopoisomeraseI) 抑制剂Irinotecan 的活性代谢产物。
- 20-O-AcetylcamptothecinCAS: 7688-64-4
20-O-Acetylcamptothecin (O-Acetylcamptothecin) 是Camptothecin 的衍生物，是拓扑异构酶 (Topoisomerase)I的抑制剂。
- β-Glu-PAB(CH2NH2)-ExatecanCAS: 3025108-11-3
β-Glu-PAB(CH2NH2)-Exatecan (Compound 9a) 是一种拓扑异构酶 I (topoisomeraseI) 的抑制剂。
- BWC0977 formicCAS: 3027162-72-4
BWC0977 formic 是一种抗菌剂，通过抑制 DNA 旋转酶 (DNA gyrase) 和拓扑异构酶 IV (topoisomerase IV) 来抑制细菌 DNA 复制。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC27009 | Belotecan | 256411-32-2 | - | ||
Belotecan (CKD-602 free base) 是 DNA topoisomerase I 抑制剂。 | |||||
| GC77343 | Dichlorogelignate | 164030-91-5 | - | ||
Dichlorogelignate (compound 4) is a selective inhibitor oftopoisomeraseII (Topo II). Dichlorogelignate has 100% inhibition at 50 μM. | |||||
| GC77368 | erythro-Austrobailignan-6 | 114127-24-1 | - | ||
erythro-Austrobailignan-6 is an orally active anti-cancer agent. erythro-Austrobailignan-6 inhibits DNAtopoisomeraseI and II activity. erythro-Austrobailignan-6 induces cellapoptosisand increases phosphorylation of p38 andJNK. | |||||
| GC78388 | Val-Ala-PAB-SN38 TFA | - | - | ||
Val-Ala-PAB-SN38 TFA 是一种 ADC 的药物-连接子偶联物 (drug-linker conjugate for ADC)，由ADC linkerVal-Ala-PAB 和 SN38 组成，SN-38是拓扑异构酶 I (TopoisomeraseI) 抑制剂Irinotecan 的活性代谢产物。 | |||||
| GC78693 | 20-O-Acetylcamptothecin | 7688-64-4 | - | ||
20-O-Acetylcamptothecin (O-Acetylcamptothecin) 是Camptothecin 的衍生物，是拓扑异构酶 (Topoisomerase)I的抑制剂。 | |||||
| GC78696 | β-Glu-PAB(CH2NH2)-Exatecan | 3025108-11-3 | - | ||
β-Glu-PAB(CH2NH2)-Exatecan (Compound 9a) 是一种拓扑异构酶 I (topoisomeraseI) 的抑制剂。 | |||||
| GC27608 | BWC0977 formic | 3027162-72-4 | - | ||
BWC0977 formic 是一种抗菌剂，通过抑制 DNA 旋转酶 (DNA gyrase) 和拓扑异构酶 IV (topoisomerase IV) 来抑制细菌 DNA 复制。 | |||||