关于 "Formyl Peptide Receptors" 的结果353+ 个结果

Matsumoto et al. conducted an affinity selection of T7 phage-displayed peptide using biotinylated CBP501, which identified this 14-mer peptide. It showed similarity to a portion of the alphaC helix of human 14-3-3e, suggesting that CBP501 may bind to this region.

Galanin-like peptide (GALP) is a 60 amino acid neuropeptide first isolated from the porcine hypothalamus and subsequently also identified in rats and humans. GALP exhibits a higher affinity (~18-fold) for the GALR2 receptor compared to the GALR1 receptor, whereas galanin is relatively non-selective. Investigations of the physiological role of GALP revealed that GALP induces food intake with a ten times higher orexigenic activity than galanin. Furthermore, GALP could affect the emotional state in the CNS. Therefore, GALP represents an orexigenic and anxiogenic peptide.

This member of the galanin family has been isolated from porcine hypothalamus. It is a 60 amino acid peptide that, unlike galanin, has a non-amidated C-terminus. GALP amino acid residues (9-21) are identical to the biologically active N-terminal (1-13) portion of galanin. Receptor binding studies revealed that GALP had a high affinity for the galanin receptor 2 (GALR2; IC?? = 0.24 nM) and a lower affinity for the GALR1 receptor (IC?? = 4.3 nM). GALP is therefore an endogenous ligand that preferentially binds the GALR2 receptor, whereas galanin is relatively non-selective.

Galanin-like peptide (GALP), first isolated from the porcine hypothalamus and subsequently also identified in rats and humans, is a 60 amino acid neuropeptide that unlike galanin, has a non-amidated C-terminus. Its amino acid residues (9-21) are identical to the biologically active N-terminal (1-13) fragment of galanin. In contrast to galanin which is relatively non-selective, receptor binding studies revealed that GALP had a high affinity for the galanin receptor 2 (GALR2) and a lower affinity for the GALR1 receptor. Furthermore, it could be demonstrated that GALP stimulates food intake with a ten fold higher orexigenic activity than galanin and may also affect emotional state in the CNS.

HCNP (Ac-AADISQWAGPL), originally purified from rat hippocampus, is a peptide capable of stimulating the acetylcholine synthesis of medial septal nuclei in vitro. HCNP may therefore be involved in the development of specific cholinergic neurons in the central nervous system.

DAPKSubstratePeptideTFA是一种合成的死亡相关蛋白激酶(DAPK)的肽底物，Km为9μM。

26Rfa, Hypothalamic Peptide, human 是一种下丘脑神经肽，属于 RFamide 肽家族，具有促食欲活性。26RFa 是一种促食欲神经肽，是孤儿 G 蛋白偶联受体 GPR103 的内源性配体。

Bim BH3, Peptide IV 是一种来自 BH3-only protein Bim 的 26 个残基肽，属于 Bcl-2 蛋白家族的促凋亡家族。

Calmodulin Binding Peptide 1 是一种来源于平滑肌肌球蛋白轻链激酶 (MLCK 肽) 的高亲和力 (pM) CaM 结合肽，能强烈抑制 IP3 诱导的 Ca2+ 释放。

Competence-Stimulating Peptide-12261，是一种十六肽，是感受刺激肽的片段。感受刺激肽是一种群体感应分子，抑制胚芽管 (GT) 形成。

PTD-p65-P1 Peptide 是一种核转录因子 NF-kappaB 抑制剂，由一个 antennapedia 衍生的膜转运肽序列 (PTD) 连接 p65-P1 构成, 选择性地抑制由各种刺激诱导的 NF-kappaB 活性。

Thioredoxin reductase peptide TFA 是硫氧还蛋白还原酶的 53–67 残基对应的多肽，用于硫氧还蛋白还原酶研究。硫氧还蛋白还原酶作为含二硫化物蛋白质的还原剂，在细胞抗氧化防御中起着重要作用。

IKKγ NBD Inhibitory Peptide是 NEMO 结合域的多肽，对应着 NEMO 氨基端α螺旋区，可以阻断 TNFα 诱导的 NF-kB 激活。

α2β1 Integrin Ligand Peptide在细胞膜表面与 α2β1 整合素受体相互作用,进入细胞介导细胞外信号。α2β1 Integrin Ligand Peptide是一种潜在的胶原受体拮抗剂。

A biomarker for chronic obstructive pulmonary disease and cystic fibrosis

Histone H1-derived Peptide 是一种磷酸肽，肽底物包含 CDK 最佳识别基序的序列。

TAT-HA2 Fusion Peptide是由HIV TAT跨膜肽和流感病毒HA2融合肽组成的双功能肽。