关于 "Oxidative Phosphorylation" 的结果26+ 个结果
- Dodecyl-TPPCAS: 15510-55-1
Dodecyl-TPP (15510-55-1) is a mitochondria-targeting agent which inhibits mitochondrial function inhibiting oxidative phosphorylation and shifting cell metabolism to glycolysis. Potently eradicates cancer stem cells (50 nm to 1 mM) selectively over normal cells. Synergizes with FDA-approved drugs such as doxycycline and niclosamide as well as natural compounds such as berberine. Selectively inhibits the growth of Gram-positive over Gram-negative bacteria.
- PPARγ phosphorylation inhibitor 1CAS: 2882975-84-8
PPARγ phosphorylation inhibitor 1 (Compound 10) 是一种有效的 PPARγ 结合剂，IC50 为 24 nM。PPARγ phosphorylation inhibitor 1 抑制 CDK5 介导的 PPARγ Ser273 磷酸化，IC50 为 160 nM。PPARγ phosphorylation inhibitor 1 几乎没有 PPARγ 激动作用。具有抗糖尿病作用。
- MARCKS Peptide(151-175), Phosphorylated
MARCKS Peptide(151-175), Phosphorylated 是一种由豆蔻酰化富丙氨酸 C 激酶底物蛋白 (MARCKS) 基本效应域片段组成的磷酸化多肽，MARCKS Peptide (151-175) 的磷酸化逆转了它对磷脂酶 C (PLC) 催化磷脂酰肌醇 -4,5- 二磷酸 (PIP2) 水解的抑制作用。
- pp60 c-src (521-533) (phosphorylated)CAS: 149299-77-4
Peptide corresponding to the pp60c-src carboxy terminal regulatory domain
- Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-D-alaninateCAS: 1627824-09-2
Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-D-alaninate (Sofosbuvir impurity 4/Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-D-alaninate) 是一种药物中间体，用于合成各种活性化合物。
- Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninateCAS: 1337529-56-2
Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate 可用于合成索非布韦 (Sofosbuvir; ) 以避免索非布韦降解杂质的产生。
- (S)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoateCAS: 1334513-02-8
(S)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate 是一种丙氨酸衍生物。
- Glutathione oxidized (L-Glutathione oxidized)CAS: 27025-41-8
Glutathione oxidized (L-Glutathione oxidized)，是抗氧化剂L-谷胱甘肽的氧化形式，作为一种信号分子，可触发抗氧化基因的激活。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC34344 | S-Gboxin | 2101317-21-7 | Others | ||
S-Gboxin, a functional analogue of Gboxin, is an oxidative phosphorylation (OXPHOS) inhibitor which inhibits growth of mouse and human glioblastoma (GBM) with IC50 of 470 nM. | |||||
| GC62564 | Mito-LND | 2361564-49-8 | Autophagy | ||
Mito-LND (Mito-Lonidamine) 是一种具有口服活性的且靶向线粒体的氧化磷酸化 (oxidative phosphorylation (OXPHOS)) 抑制剂。Mito-LND 抑制线粒体生物能，刺激活性氧 (reactive oxygen species) 的形成，并诱导肺癌细胞自噬细胞死亡。 | |||||
| GB40185 | Dodecyl-TPP | 15510-55-1 | - | ||
Dodecyl-TPP (15510-55-1) is a mitochondria-targeting agent which inhibits mitochondrial function inhibiting oxidative phosphorylation and shifting cell metabolism to glycolysis. Potently eradicates cancer stem cells (50 nm to 1 mM) selectively over normal cells. Synergizes with FDA-approved drugs such as doxycycline and niclosamide as well as natural compounds such as berberine. Selectively inhibits the growth of Gram-positive over Gram-negative bacteria. | |||||
| GC75352 | PPARγ phosphorylation inhibitor 1 | 2882975-84-8 | - | ||
PPARγ phosphorylation inhibitor 1 (Compound 10) 是一种有效的 PPARγ 结合剂，IC50 为 24 nM。PPARγ phosphorylation inhibitor 1 抑制 CDK5 介导的 PPARγ Ser273 磷酸化，IC50 为 160 nM。PPARγ phosphorylation inhibitor 1 几乎没有 PPARγ 激动作用。具有抗糖尿病作用。 | |||||
| GB52944 | 1-[bromomethyl(ethoxy)phosphoryl]oxyethane | 66197-72-6 | - | ||
| GC36539 | MARCKS Peptide(151-175), Phosphorylated | - | Peptides | ||
MARCKS Peptide(151-175), Phosphorylated 是一种由豆蔻酰化富丙氨酸 C 激酶底物蛋白 (MARCKS) 基本效应域片段组成的磷酸化多肽，MARCKS Peptide (151-175) 的磷酸化逆转了它对磷脂酶 C (PLC) 催化磷脂酰肌醇 -4,5- 二磷酸 (PIP2) 水解的抑制作用。 | |||||
| GC17137 | pp60 c-src (521-533) (phosphorylated) | 149299-77-4 | Src | ||
Peptide corresponding to the pp60c-src carboxy terminal regulatory domain | |||||
| GB58974 | Isopropyl (chloro(phenoxy)phosphoryl)-D-alaninate | 926309-10-6 | - | ||
| GC77817 | Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-D-alaninate | 1627824-09-2 | - | ||
Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-D-alaninate (Sofosbuvir impurity 4/Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-D-alaninate) 是一种药物中间体，用于合成各种活性化合物。 | |||||
| GC65325 | Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate | 1337529-56-2 | Peptides | ||
Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate 可用于合成索非布韦 (Sofosbuvir; ) 以避免索非布韦降解杂质的产生。 | |||||
| GB50613 | (2S)-Isopropyl 2-(((perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate | 1256490-52-4 | - | ||
| GC68085 | (S)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate | 1334513-02-8 | Peptides | ||
(S)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate 是一种丙氨酸衍生物。 | |||||
| GB61859 | Tris((bis((2-ethylhexyl)oxy)phosphoryl)oxy)(isopropoxy)titanium | 65345-34-8 | - | ||
| GC31353 | Glutathione oxidized (L-Glutathione oxidized) | 27025-41-8 | Peptides | ||
Glutathione oxidized (L-Glutathione oxidized)，是抗氧化剂L-谷胱甘肽的氧化形式，作为一种信号分子，可触发抗氧化基因的激活。 | |||||
| GC19423 | Triphenylphosphine oxide | 791-28-6 | - | ||
Coordinating solvent used to activate crystallization | |||||
| GC43584 | Ebselen Oxide | 104473-83-8 | Reactive Nitrogen Species | ||
Oxidized form of ebselen, lacking antioxidant activity | |||||
| GB59135 | Lithium oxide | 12057-24-8 | - | ||
| GC17811 | Albendazole Oxide | 54029-12-8 | Parasite | ||
A benzimidazole agent with anthelmintic and antiparasitic effects | |||||
| GC64986 | Linalool oxide | 60047-17-8 | Others | ||
Linalool oxide 是小麦伸长植株的次生代谢产物，具有抗伤害和抗惊厥作用。Linalool oxide 具有抗焦虑活性。 | |||||
| GC45245 | (-)-Caryophyllene oxide | 1139-30-6 | Endogenous Metabolite | ||
A bicyclic sesquiterpene | |||||
| GB61835 | Triphenylantimony oxide | 4756-75-6 | - | ||
| GD19423 | Polyethylene oxide | 68441-17-8 | - | ||
| GB56940 | Aluminum oxide | 1344-28-1 | - | ||
| GC49845 | Piribedil N-oxide | 53954-71-5 | Drug Metabolite | ||
A metabolite of piribedil | |||||