关于 "Adenosine Deaminase" 的结果20+ 个结果
- Adenosine deaminaseCAS: 9026-93-1
腺苷脱氨酶(Adenosine deaminase,ADA)是参与嘌呤代谢途径的关键酶,对腺苷和脱氧腺苷具有不可逆脱氨作用,分别转化为肌苷和脱氧肌苷。
- 2′-O-(2-Methoxyethyl)guanosineCAS: 473278-54-5
2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside.
- N6-BenzyladenosineCAS: 4294-16-0
DNPH1i (N6-benzyladenosine,BAPR) is a competitive inhibitor of adenosine deaminase(ADA) from L-1210 cells in axenic culture as well as a potent antiproliferative agent in vitro and in vivo.
- HibifolinCAS: 55366-56-8
Hibifolin (Gossypetin-8-O-β-D-glucuronide) is a flavonol glycoside and acts as a potential inhibitor of adenosine deaminase (ADA) with a Ki of 49.92 μM. Hibifolin prevents β-amyloid-induced neurotoxicity in cultured cortical neurons.
- EHNA HClCAS: 51350-19-7
EHNA (51350-19-7) inhibits phosphodiesterase 2 (PDE2) (IC50 = 0.8 - 5.5 µM in a variety of tissues and species) over PDE1, PDE3, or PDE4 (IC50 values > 100 µM). It also inhibits adenosine deaminase (ADA), IC50 = 1.2 and 1.5 µM in human RBCs and astrocytoma cells, respectively, which may be responsible for its ability to induce apoptosis in malignant pleural mesothelioma cell lines. Because it blocks breakdown of adenosine to inosine and hypoxanthine, EHNA prevents formation of free radical substrates, protecting against cardiac reperfusion-mediated injury. It inhibits differentiation and maintains expression of pluripotency markers in hESCs, but not through inhibition of PDEs or ADA.
- Deaminase inhibitor-1CAS: 397878-17-0
Deaminase inhibitor-1 是 APOBEC3G DNA 脱氨酶的小分子抑制剂,IC50 为 18.9 μM。
- Adenosine-5'-diphosphateCAS: 58-64-0
Adenosine-5'-diphosphate是 P2Y1、P2Y12、P2Y13 等嘌呤能 P2Y 受体的天然激动剂,可直接结合并触发下游信号级联。
- L-AdenosineCAS: 3080-29-3
L-Adenosine 是一种代谢稳定的对映异构体类似物,也是一种潜在的探针。L-Adenosine 具有弱抑制性腺苷脱氨酶 (ADA) 活性,Ki 值为 385 μM。L-Adenosine 可用于腺苷摄取和积累的研究。
- Adenosine-d2CAS: 82741-17-1
Adenosine-d2 是 Adenosine 的氘代物。 Adenosine (Adenine riboside) 是一种普遍存在的内源性分泌物,是通过四种G蛋白偶联受体(A1、A2A、A2B 和 A3)的起作用。Adenosine 几乎影响细胞生理学的所有方面,包括神经元活动、血管功能、血小板聚集和血细胞调节。
- Adenosine-13C5CAS: 159496-13-6
Adenosine-13C5 是 13C 标记的 Adenosine。 Adenosine (Adenine riboside) 是一种普遍存在的内源性分泌物,是通过四种G蛋白偶联受体(A1、A2A、A2B 和 A3)的起作用。Adenosine 几乎影响细胞生理学的所有方面,包括神经元活动、血管功能、血小板聚集和血细胞调节。
- Adenosine 5′-diphosphoriboseCAS: 20762-30-5
Adenosine 5′-diphosphoribose(ADP核糖)由连接到核糖糖的腺嘌呤碱基组成,核糖糖又连接到两个磷酸基团。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC35250 | Adenosine deaminase | 9026-93-1 | Adenosine Deaminase | ||
腺苷脱氨酶(Adenosine deaminase,ADA)是参与嘌呤代谢途径的关键酶,对腺苷和脱氧腺苷具有不可逆脱氨作用,分别转化为肌苷和脱氧肌苷。 | |||||
| GP21354 | ADAL Human | - | Deaminase | ||
Adenosine Deaminase-Like Human Recombinant | |||||
| GP21355 | ADAT1 Human | - | Deaminase | ||
Adenosine Deaminase tRNA-Specific 1 Human Recombinant | |||||
| GP21356 | ADAT2 Human | - | Deaminase | ||
Adenosine Deaminase, tRNA-specific 2 Human Recombinant | |||||
| GC61938 | 2′-O-(2-Methoxyethyl)guanosine | 473278-54-5 | Biochemical Assay Reagents | ||
2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. | |||||
| GC67272 | N6-Benzyladenosine | 4294-16-0 | Apoptosis | ||
DNPH1i (N6-benzyladenosine,BAPR) is a competitive inhibitor of adenosine deaminase(ADA) from L-1210 cells in axenic culture as well as a potent antiproliferative agent in vitro and in vivo. | |||||
| GC60899 | Hibifolin | 55366-56-8 | Adenosine Deaminase | ||
Hibifolin (Gossypetin-8-O-β-D-glucuronide) is a flavonol glycoside and acts as a potential inhibitor of adenosine deaminase (ADA) with a Ki of 49.92 μM. Hibifolin prevents β-amyloid-induced neurotoxicity in cultured cortical neurons. | |||||
| GB40191 | EHNA HCl | 51350-19-7 | - | ||
EHNA (51350-19-7) inhibits phosphodiesterase 2 (PDE2) (IC50 = 0.8 - 5.5 µM in a variety of tissues and species) over PDE1, PDE3, or PDE4 (IC50 values > 100 µM). It also inhibits adenosine deaminase (ADA), IC50 = 1.2 and 1.5 µM in human RBCs and astrocytoma cells, respectively, which may be responsible for its ability to induce apoptosis in malignant pleural mesothelioma cell lines. Because it blocks breakdown of adenosine to inosine and hypoxanthine, EHNA prevents formation of free radical substrates, protecting against cardiac reperfusion-mediated injury. It inhibits differentiation and maintains expression of pluripotency markers in hESCs, but not through inhibition of PDEs or ADA. | |||||
| GC75359 | Deaminase inhibitor-1 | 397878-17-0 | - | ||
Deaminase inhibitor-1 是 APOBEC3G DNA 脱氨酶的小分子抑制剂,IC50 为 18.9 μM。 | |||||
| GC35420 | ATP | 56-65-5 | Endogenous Metabolite | ||
ATP是代谢反应中底物激活的磷酸基供体,用于生物合成细胞内第二信使环状腺苷酸单磷酸(cAMP),并作为真正的细胞外信使介导细胞间通讯。 | |||||
| GC11969 | Adenosine-5'-diphosphate | 58-64-0 | Endogenous Metabolite | ||
Adenosine-5'-diphosphate是 P2Y1、P2Y12、P2Y13 等嘌呤能 P2Y 受体的天然激动剂,可直接结合并触发下游信号级联。 | |||||
| GC14106 | Adenosine | 58-61-7 | Endogenous Metabolite | ||
Adenosine是一种内源性神经调节物质,包含腺嘌呤,通过β-N9-糖苷键与核糖分子(呋喃核糖)部分连接。 | |||||
| GC66645 | L-Adenosine | 3080-29-3 | Adenosine Deaminase | ||
L-Adenosine 是一种代谢稳定的对映异构体类似物,也是一种潜在的探针。L-Adenosine 具有弱抑制性腺苷脱氨酶 (ADA) 活性,Ki 值为 385 μM。L-Adenosine 可用于腺苷摄取和积累的研究。 | |||||
| GC68625 | Adenosine-d2 | 82741-17-1 | Nucleoside Antimetabolite/Analogue | ||
Adenosine-d2 是 Adenosine 的氘代物。 Adenosine (Adenine riboside) 是一种普遍存在的内源性分泌物,是通过四种G蛋白偶联受体(A1、A2A、A2B 和 A3)的起作用。Adenosine 几乎影响细胞生理学的所有方面,包括神经元活动、血管功能、血小板聚集和血细胞调节。 | |||||
| GC73524 | Alpha-Adenosine | 5682-25-7 | Nucleoside Antimetabolite/Analogue | ||
Alpha-Adenosine是嘌呤核苷类似物。 | |||||
| GD01654 | Adenosine 3′-monophosphate | 84-21-9 | - | ||
Adenosine 3′-monophosphate (3′-AMP) 是一种核苷酸,是一种环 AMP 产生激动剂。 | |||||
| GC76025 | Adenosine-13C5 | 159496-13-6 | - | ||
Adenosine-13C5 是 13C 标记的 Adenosine。 Adenosine (Adenine riboside) 是一种普遍存在的内源性分泌物,是通过四种G蛋白偶联受体(A1、A2A、A2B 和 A3)的起作用。Adenosine 几乎影响细胞生理学的所有方面,包括神经元活动、血管功能、血小板聚集和血细胞调节。 | |||||
| GC19630 | Adenosine 2′-monophosphate | 130-49-4 | Endogenous Metabolite | ||
腺苷 &2#8242;-一磷酸 (2'-AMP) 被细胞外 2',3'-CAMP 转化。 | |||||
| GC38884 | Adenosine amine congener | 96760-69-9 | Adenosine Receptor | ||
An adenosine A1 receptor agonist | |||||
| GC72762 | Adenosine 5′-diphosphoribose | 20762-30-5 | Endogenous Metabolite | ||
Adenosine 5′-diphosphoribose(ADP核糖)由连接到核糖糖的腺嘌呤碱基组成,核糖糖又连接到两个磷酸基团。 | |||||
