关于 "Aurora Kinase" 的结果16+ 个结果
筛选:Ubiquitination/ Proteasome×
- Calmodulin-Dependent Protein Kinase II(290-309) acetate
Calmodulin-DependentProteinKinaseII(290-309)acetate是有效的CaMK拮抗剂，抑制抑制Ca2+/钙调蛋白依赖性蛋白激酶II的IC50值为52nM。
- LY 294002 hydrochlorideCAS: 934389-88-5
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
- MLN8237 (Alisertib)CAS: 1028486-01-2
Alisertib (MLN8237) 作为一种在研、可口服的选择性极光 A 激酶抑制剂，通常用于治疗实体瘤和血液系统恶性肿瘤。
- VX-680 (MK-0457,Tozasertib)CAS: 639089-54-6
VX-680 (MK-0457,Tozasertib)是一种有效的Aurora激酶抑制剂，对Aurora A/B/C的K i 值分别为0.6、18、4.6nM，具有抗癌活性。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC15217 | Danusertib (PHA-739358) | 827318-97-8 | Autophagy | ||
A pan-Aurora kinase and Abl inhibitor | |||||
| GC31170 | Calmodulin-Dependent Protein Kinase II 290-309 | 115044-69-4 | Peptides | ||
A CaMKII inhibitor | |||||
| GC61521 | Calmodulin-Dependent Protein Kinase II(290-309) acetate | - | Peptides | ||
Calmodulin-DependentProteinKinaseII(290-309)acetate是有效的CaMK拮抗剂，抑制抑制Ca2+/钙调蛋白依赖性蛋白激酶II的IC50值为52nM。 | |||||
| GC50253 | PF 543 hydrochloride | 1706522-79-3 | LPL Receptor | ||
A potent inhibitor of SPHK1 | |||||
| GC13202 | D4476 | 301836-43-1 | Autophagy | ||
Inhibitor of CK1 and ALK5 | |||||
| GC50009 | LY 294002 hydrochloride | 934389-88-5 | Autophagy | ||
Prototypical PI 3-kinase inhibitor; also inhibits other kinases | |||||
| GC16499 | Sorafenib Tosylate | 475207-59-1 | Other Apoptosis | ||
A multi-kinase inhibitor | |||||
| GC17196 | Hesperadin | 422513-13-1 | Parasite | ||
Hesperadin是一种竞争性ATP结合抑制剂，对Aurora B激酶的IC50为250nM。 | |||||
| GC14683 | Sunitinib malate | 341031-54-7 | Autophagy | ||
A multi-kinase inhibitor | |||||
| GC16327 | Pazopanib (GW-786034) | 444731-52-6 | Autophagy | ||
A multi-kinase inhibitor | |||||
| GC12690 | MLN8237 (Alisertib) | 1028486-01-2 | Other Apoptosis | ||
Alisertib (MLN8237) 作为一种在研、可口服的选择性极光 A 激酶抑制剂，通常用于治疗实体瘤和血液系统恶性肿瘤。 | |||||
| GC11549 | VX-680 (MK-0457,Tozasertib) | 639089-54-6 | Autophagy | ||
VX-680 (MK-0457,Tozasertib)是一种有效的Aurora激酶抑制剂，对Aurora A/B/C的Ki值分别为0.6、18、4.6nM，具有抗癌活性。 | |||||
| GC14651 | Reversine | 656820-32-5 | Autophagy | ||
Reversine是一种靶向Aurora A激酶、Aurora B激酶和MPS1（Monopolar Spindle 1）激酶的非特异性、具有口服活性的小分子抑制剂。Reversine常用于细胞分化和多种癌症的研究。 | |||||
| GC10638 | AT9283 | 896466-04-9 | Autophagy | ||
A broad spectrum kinase inhibitor | |||||
| GC33732 | Syntide 2 | 108334-68-5 | Peptides | ||
A protein kinase substrate | |||||
| GC37886 | Vandetanib trifluoroacetate | 338992-53-3 | Autophagy | ||
A multi-kinase inhibitor | |||||