关于 "ALK" 的结果32+ 个结果
筛选:Tyrosine Kinase×
- ALK inhibitor 1CAS: 761436-81-1
ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor which can inhibit testis-specific serine/threonine kinase (TSSK2; IC50=31 nM) and focal adhesion kinase (FAK; IC50=2 nM).
- ALK kinase inhibitor-1CAS: 1462949-64-9
ALK kinase inhibitor-1 是一种间变性淋巴瘤激酶 ALK 抑制剂，详细信息请参考专利文献 US20130261106A1 中的化合物 I-202。
- SIAIS164018 hydrochloride
SIAIS164018 hydrochloride是一种基于protac的ALK和EGFR降解剂，ALK和ALK G1202R的IC50值分别为2.5 nM和6.6 nM。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC35287 | ALK inhibitor 1 | 761436-81-1 | ALK | ||
ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor which can inhibit testis-specific serine/threonine kinase (TSSK2; IC50=31 nM) and focal adhesion kinase (FAK; IC50=2 nM). | |||||
| GC17376 | ALK inhibitor 2 | 761438-38-4 | ALK | ||
An inhibitor of TSSK2 | |||||
| GC35290 | ALK-IN-6 | 2055821-33-3 | ALK | ||
ALK-IN-6 (compound 11) 是口服有效的，间变性淋巴瘤激酶 (ALK) 的抑制剂，其对野生型 ALK、ALK F1196M 和ALK F1174L 的 IC50 值分别为 71 nM、18.72 nM 和36.81 nM。 | |||||
| GC35289 | ALK-IN-5 | 2351929-66-1 | ALK | ||
ALK-IN-5 是一种高效选择性的，可渗透大脑屏障的 (ALK) 激酶抑制剂，IC50 值为 2.9 nM。 | |||||
| GC73642 | ALK-IN-26 | 2447607-85-2 | ALK | ||
ALK-IN-26是ALK抑制剂，对ALK酪氨酸激酶的IC50值为7.0 μM。 | |||||
| GC73883 | ALK-IN-28 | 1108743-80-1 | ALK | ||
ALK-IN-28（化合物22）是间变性淋巴瘤激酶（ALK）的抑制剂。 | |||||
| GC63387 | ALK kinase inhibitor-1 | 1462949-64-9 | ALK | ||
ALK kinase inhibitor-1 是一种间变性淋巴瘤激酶 ALK 抑制剂，详细信息请参考专利文献 US20130261106A1 中的化合物 I-202。 | |||||
| GC14189 | AZD-3463 | 1356962-20-3 | Autophagy | ||
An ALK and IGF-1R inhibitor | |||||
| GC19508 | BLU-782 | 2141955-96-4 | ALK | ||
BLU-782 是一种口服精准疗法，专门设计用于选择性靶向突变体 ALK2。 | |||||
| GC64013 | ZX-29 | 2254805-62-2 | Autophagy | ||
ZX-29 is a potent and selective ALK inhibitor with an IC50s of 2.1, 1.3 and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively. | |||||
| GC14552 | LDK378 | 1032900-25-6 | IGF1R | ||
An ALK inhibitor | |||||
| GC14446 | ASP3026 | 1097917-15-1 | ALK | ||
An ALK inhibitor | |||||
| GC36222 | HG-14-10-04 | 1356962-34-9 | ALK | ||
An ALK inhibitor | |||||
| GC19063 | Belizatinib | 1357920-84-3 | Trk | ||
An ALK inhibitor | |||||
| GC19140 | X-376 | 1365267-27-1 | c-MET | ||
An ALK inhibitor | |||||
| GC32864 | Ensartinib hydrochloride (X-396 hydrochloride) | 2137030-98-7 | c-MET | ||
An ALK inhibitor | |||||
| GC33190 | Ensartinib (X-396) | 1370651-20-9 | c-MET | ||
An ALK inhibitor | |||||
| GC16694 | TAE684 (NVP-TAE684) | 761439-42-3 | Other Apoptosis | ||
A selective ALK inhibitor | |||||
| GC17283 | AP26113 | 1197958-12-5 | ALK | ||
A potent ALK inhibitor | |||||
| GC73129 | SIAIS164018 hydrochloride | - | ALK | ||
SIAIS164018 hydrochloride是一种基于protac的ALK和EGFR降解剂，ALK和ALK G1202R的IC50值分别为2.5 nM和6.6 nM。 | |||||
| GC15145 | CEP-28122 | 1022958-60-6 | ALK | ||
An orally active ALK inhibitor | |||||
| GC35652 | CEP-28122 mesylate salt | - | ALK | ||
An orally active ALK inhibitor | |||||
| GC19084 | Brigatinib | 1197953-54-0 | ALK | ||
An orally bioavailable ALK inhibitor | |||||
| GC16025 | CH5424802 | 1256580-46-7 | ALK | ||
An orally available inhibitor of ALK | |||||