关于 "Topoisomerase" 的结果47+ 个结果
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- Topoisomerase I inhibitor 8CAS: 210346-40-0
Topoisomerase I inhibitor 8 是一种强效 topoisomerase I 抑制剂。Topoisomerase I inhibitor 8 是一种喜树碱六环类似物，对肿瘤细胞有毒性。
Topoisomerase - Topoisomerase IIα-IN-8CAS: 1251578-67-2
Topoisomerase IIα-IN-8（化合物15）是一种弱的人DNA拓扑异构酶IIa （htIIa）抑制剂，IC50为462±38.0 μM。
Topoisomerase - Topoisomerase II inhibitor 14CAS: 305343-00-4
Topoisomerase II inhibitor 14（化合物2f）是拓扑异构酶II的强效抑制剂，具有抗癌活性。
- Dexrazoxane HCl (ICRF-187, ADR-529)CAS: 149003-01-0
Topoisomerase IIα inhibitor and intracellular ion chelator
- Proscillaridin ACAS: 466-06-8
Proscillaridin A 是强力的拓扑异构酶 I 和 II topoisomerase I/II 抑制剂，抑制拓扑异构酶 I 和 II 的 IC50 值分别为 30 nM 和 100 nM。
Topoisomerase
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC70044 | Topoisomerase I inhibitor 8 | 210346-40-0 | Topoisomerase | ||
Topoisomerase I inhibitor 8 是一种强效 topoisomerase I 抑制剂。Topoisomerase I inhibitor 8 是一种喜树碱六环类似物，对肿瘤细胞有毒性。 | |||||
| GC74656 | Topoisomerase IIα-IN-8 | 1251578-67-2 | Topoisomerase | ||
Topoisomerase IIα-IN-8（化合物15）是一种弱的人DNA拓扑异构酶IIa （htIIa）抑制剂，IC50为462±38.0 μM。 | |||||
| GC74684 | Topoisomerase II inhibitor 14 | 305343-00-4 | Apoptosis | ||
Topoisomerase II inhibitor 14（化合物2f）是拓扑异构酶II的强效抑制剂，具有抗癌活性。 | |||||
| GC13544 | Voreloxin | 175414-77-4 | Other Apoptosis | ||
An inhibitor of topoisomerase II | |||||
| GC15617 | Etoposide | 33419-42-0 | Other Apoptosis | ||
Etoposide（VP-16）是一种非特异性拓扑异构酶II（Topoisomerase II）抑制剂，IC50值为59.2 μM。 | |||||
| GC11019 | Amonafide | 69408-81-7 | Topoisomerase | ||
A DNA-intercalating topoisomerase II poison | |||||
| GC10686 | Epirubicin HCl | 56390-09-1 | DNA/RNA Synthesis | ||
Epirubicin HCl是一种具有口服活性的DNA topoisomerase II特异性抑制剂，IC50为12μM。 | |||||
| GC11619 | Dexrazoxane HCl (ICRF-187, ADR-529) | 149003-01-0 | Others | ||
Topoisomerase IIα inhibitor and intracellular ion chelator | |||||
| GC16084 | Teniposide | 29767-20-2 | Topoisomerase | ||
A topoisomerase II poison | |||||
| GC12326 | Amsacrine | 51264-14-3 | Autophagy | ||
A topoisomerase II poison | |||||
| GC11747 | Amsacrine hydrochloride | 54301-15-4 | Autophagy | ||
A topoisomerase II poison | |||||
| GC11048 | Irinotecan HCl Trihydrate | 136572-09-3 | Autophagy | ||
A potent inhibitor of DNA topoisomerase I | |||||
| GC14363 | Mitoxantrone HCl | 70476-82-3 | SARS-CoV | ||
An inhibitor of DNA topoisomerase IIα and HIV-1 integrase | |||||
| GC12503 | Pixantrone | 144510-96-3 | Topoisomerase | ||
A DNA topoisomerase II inhibitor | |||||
| GN10449 | SN-38 (NK012) | 86639-52-3 | Autophagy | ||
A potent inhibitor of DNA topoisomerase I | |||||
| GC15853 | Genz-644282 | 529488-28-6 | Topoisomerase | ||
An inhibitor of topoisomerase I | |||||
| GC10098 | (S)-10-Hydroxycamptothecin | 19685-09-7 | Other Apoptosis | ||
A DNA topoisomerase I inhibitor | |||||
| GC44651 | Pixantrone (maleate) | 144675-97-8 | Topoisomerase | ||
A DNA topoisomerase II inhibitor | |||||
| GC44809 | Rebeccamycin | 93908-02-2 | ADC Cytotoxin | ||
A DNA topoisomerase I inhibitor | |||||
| GC45009 | Temafloxacin | 108319-06-8 | Pneumonia | ||
A DNA topoisomerase inhibitor | |||||
| GC35997 | Epirubicin | 56420-45-2 | Other Apoptosis | ||
Epirubicin是一种具有口服活性的DNA topoisomerase II特异性抑制剂，IC50为12μM。 | |||||
| GC36329 | Irinotecan hydrochloride | 100286-90-6 | Autophagy | ||
A potent inhibitor of DNA topoisomerase I | |||||
| GC36549 | Mauritianin | 109008-28-8 | Topoisomerase | ||
A flavonoid glycoside and DNA topoisomerase I inhibitor | |||||
| GC39425 | Proscillaridin A | 466-06-8 | Topoisomerase | ||
Proscillaridin A 是强力的拓扑异构酶 I 和 II topoisomerase I/II 抑制剂，抑制拓扑异构酶 I 和 II 的 IC50 值分别为 30 nM 和 100 nM。 | |||||