GlpBio

Dexrazoxane HCl (ICRF-187, ADR-529)

目录号: GC11619纯度: >98.50%同义词: 右雷佐生盐酸盐; ICRF-187 hydrochloride; ADR-529 hydrochloride; NSC-169780 hydrochloride
Topoisomerase IIα inhibitor and intracellular ion chelator
Dexrazoxane HCl (ICRF-187, ADR-529)
Cas No.: 149003-01-0
规格价格库存数量操作
10mg¥350.00现货
1
50mg¥686.00现货
1
100mg¥945.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Dexrazoxane hydrochloride (ICRF-187 hydrochloride) is a cardioprotective agent.

References:
[1]. Hasinoff BB. The use of dexrazoxane for the prevention of anthracycline extravasation injury. Expert Opin Investig Drugs. 2008 Feb;17(2):217-23.
[2]. Jones RL. Utility of dexrazoxane for the reduction of anthracycline-induced cardiotoxicity. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1311-7.
[3]. Lipshultz SE, Scully RE, Lipsitz SR et al. Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial. Lancet Oncol. 2010 Oct;11(10):950-61.

产品文档 Product Documents

Purity:>98.50%

化学性质Chemical Properties

CAS 号
149003-01-0
同义词
右雷佐生盐酸盐; ICRF-187 hydrochloride; ADR-529 hydrochloride; NSC-169780 hydrochloride
化学名
4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;hydrochloride
SMILES
CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl
分子式
C11H16N4O4.HCl
分子量
304.73 g/mol
溶解性
≥ 15.24mg/mL in DMSO
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol