关于 "c-RET" 的结果8 个结果
筛选:Signaling Pathways×
- Urolithin CCAS: 165393-06-6
UrolithinC，是鞣花酸的多酚类肠道微生物代谢产物，是胰岛素分泌(insulinsecretion)的葡萄糖依赖性激活剂。UrolithinC是一种L型Ca2+通道开放剂，可增强Ca2+的流入。UrolithinC通过线粒体介导的途径诱导细胞凋亡(apoptosis)，并刺激活性氧(ROS)的形成。
- YUM70CAS: 423145-35-1
YUM70 is a potent inhibitor of glucose-regulated protein 78 (GRP78) inhibitor with an IC50 of 1.5 μM. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.Although YUM70 inhibits GRP78 enzymatic activity, it increases the expression of GRP78 by increasing the chaperone translation mechanism.
- DantroleneCAS: 7261-97-4
Dantrolene sodium(F 440) acts as a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC48327 | Secretin (rat) (trifluoroacetate salt) | - | Neuroendocrinology | ||
A neuropeptide hormone | |||||
| GC39798 | Scoulerine | 6451-73-6 | Microtubule/Tubulin | ||
A benzylisoquinoline alkaloid with diverse biological activities | |||||
| GC60377 | Urolithin C | 165393-06-6 | Reactive Oxygen Species | ||
UrolithinC，是鞣花酸的多酚类肠道微生物代谢产物，是胰岛素分泌(insulinsecretion)的葡萄糖依赖性激活剂。UrolithinC是一种L型Ca2+通道开放剂，可增强Ca2+的流入。UrolithinC通过线粒体介导的途径诱导细胞凋亡(apoptosis)，并刺激活性氧(ROS)的形成。 | |||||
| GC45459 | GHRP-6 (acetate) | 145177-42-0 | Behavioral Neuroscience | ||
A growth hormone secretagogue and GHS-R agonist | |||||
| GC43763 | GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (trifluoroacetate salt) | - | Endocrinology and Hormones | ||
An incretin hormone | |||||
| GC62388 | YUM70 | 423145-35-1 | Apoptosis | ||
YUM70 is a potent inhibitor of glucose-regulated protein 78 (GRP78) inhibitor with an IC50 of 1.5 μM. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.Although YUM70 inhibits GRP78 enzymatic activity, it increases the expression of GRP78 by increasing the chaperone translation mechanism. | |||||
| GC65503 | Dantrolene | 7261-97-4 | Others | ||
Dantrolene sodium(F 440) acts as a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. | |||||
| GC25848 | RH01687 | 302901-13-9 | Others | ||
RH01687 is a potent β-cell protector that exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress. | |||||