关于 "Topoisomerase" 的结果8 个结果
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- Topoisomerase II inhibitor 14CAS: 305343-00-4
Topoisomerase II inhibitor 14（化合物2f）是拓扑异构酶II的强效抑制剂，具有抗癌活性。
- Etoposide phosphateCAS: 117091-64-2
Etoposidephosphate(BMY-40481)是一种有效的抗癌(anti-cancer)化疗试剂和一种选择性拓扑异构酶II(topoisomeraseII)抑制剂，可以防止DNA链的重新连接。Etoposidephosphate是依托泊苷的磷酸酯前药，被认为与Etoposide活性相当。Etoposidephosphate诱导细胞周期阻滞、凋亡(apoptosis)和自噬(autophagy)。
- PyrazoloacridineCAS: 99009-20-8
Pyrazoloacridine(NSC366140)具有抗癌活性，抑制拓扑异构酶1和2的活性(topoisomerases1and2)。Pyrazoloacridine(NSC366140)对K562髓系白血病细胞中的IC50值为1.25μM(24h)。
- 20R-CamptothecinCAS: 110351-92-3
20R-Camptothecin, one of Camptothecin Derivatives, has little or no effect on topoisomerase I, in contrast to the natural S isomer
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC74684 | Topoisomerase II inhibitor 14 | 305343-00-4 | Apoptosis | ||
Topoisomerase II inhibitor 14（化合物2f）是拓扑异构酶II的强效抑制剂，具有抗癌活性。 | |||||
| GC45009 | Temafloxacin | 108319-06-8 | Pneumonia | ||
A DNA topoisomerase inhibitor | |||||
| GC60826 | Etoposide phosphate | 117091-64-2 | Autophagy | ||
Etoposidephosphate(BMY-40481)是一种有效的抗癌(anti-cancer)化疗试剂和一种选择性拓扑异构酶II(topoisomeraseII)抑制剂，可以防止DNA链的重新连接。Etoposidephosphate是依托泊苷的磷酸酯前药，被认为与Etoposide活性相当。Etoposidephosphate诱导细胞周期阻滞、凋亡(apoptosis)和自噬(autophagy)。 | |||||
| GC61224 | Pyrazoloacridine | 99009-20-8 | Apoptosis | ||
Pyrazoloacridine(NSC366140)具有抗癌活性，抑制拓扑异构酶1和2的活性(topoisomerases1and2)。Pyrazoloacridine(NSC366140)对K562髓系白血病细胞中的IC50值为1.25μM(24h)。 | |||||
| GC18751 | Reticulol | 26246-41-3 | Topoisomerase | ||
A cAMP phosphodiesterase and DNA topoisomerase I inhibitor | |||||
| GC46113 | CAY10744 | 2375613-31-1 | Apoptosis | ||
A topoisomerase II-α poison | |||||
| GC42783 | Ametantrone | 64862-96-0 | Topoisomerase | ||
An inhibitor of topoisomerase II | |||||
| GC25007 | 20R-Camptothecin | 110351-92-3 | Others | ||
20R-Camptothecin, one of Camptothecin Derivatives, has little or no effect on topoisomerase I, in contrast to the natural S isomer | |||||