关于 "Aurora Kinase" 的结果44+ 个结果
筛选:Signaling Pathways×
- TrkB Agonist Prodrug R13CAS: 1609067-49-3
TrkB Agonist Prodrug R13（R13）是原肌球蛋白相关激酶B（TrkB）激活剂7,8-二羟基黄酮的前药形式。
- PKG Inhibitor (trifluoroacetate salt)
PKG Inhibitor (trifluoroacetate salt)是一种特定的cGMP依赖性PKG抑制剂Ki=86μM。
- LY 294002 hydrochlorideCAS: 934389-88-5
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
- AMG PERK 44 (hydrochloride)
AMG PERK 44 is a protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 6 nM).
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC91977 | TrkB Agonist Prodrug R13 | 1609067-49-3 | Behavioral Neuroscience | ||
TrkB Agonist Prodrug R13（R13）是原肌球蛋白相关激酶B（TrkB）激活剂7,8-二羟基黄酮的前药形式。 | |||||
| GC44654 | PKCα (C2-4) Inhibitor Peptide | - | Signaling Pathways | ||
A PKCα inhibitor | |||||
| GC43219 | Cdk2 Inhibitor II | 222035-13-4 | Signaling Pathways | ||
Selective and potent inhibitor of Cdk2 | |||||
| GC44880 | SD 1029 | 118372-34-2 | Hepatitis | ||
A JAK2 inhibitor | |||||
| GC19508 | BLU-782 | 2141955-96-4 | ALK | ||
BLU-782 是一种口服精准疗法，专门设计用于选择性靶向突变体 ALK2。 | |||||
| GC92078 | PKG Inhibitor (trifluoroacetate salt) | - | cGMP | ||
PKG Inhibitor (trifluoroacetate salt)是一种特定的cGMP依赖性PKG抑制剂Ki=86μM。 | |||||
| GC42933 | Binucleine 2 | 220088-42-6 | Cytoskeleton & Motor Proteins | ||
An inhibitor of Drosophila Aurora B kinase | |||||
| GC50009 | LY 294002 hydrochloride | 934389-88-5 | Autophagy | ||
Prototypical PI 3-kinase inhibitor; also inhibits other kinases | |||||
| GC48971 | AZD 1152 (hydrochloride) | 722543-50-2 | Aurora Kinase | ||
A prodrug for a potent Aurora B inhibitor | |||||
| GC16157 | 740 Y-P | 1236188-16-1 | PI3K | ||
740 Y-P是一种PI3K激活剂，浓度为20μM 。 | |||||
| GC63707 | JB170 | 2705844-82-0 | PROTAC | ||
JB170 是一种强效且高度特异性的 PROTAC 介导的 AURORA-A 降解剂 (DC50=28 nM)，通过将 Alisertib 连接至 Cereblon配体 Thalidomide 而形成。JB170 优先结合 AURORA-A (EC50=193 nM) 而不是 AURORA-B (EC50=1.4µM)。JB170 介导的 S 期阻滞是由 AURORA-A 耗竭引起的。JB170 对 AURORA-A 激酶的非催化功能具有很好的抑制能力。 | |||||
| GC91790 | AMG PERK 44 (hydrochloride) | - | Other Signal Transduction | ||
AMG PERK 44 is a protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 6 nM). | |||||
| GC18677 | YMU1 | 902589-96-2 | p53 | ||
A thymidylate kinase inhibitor | |||||
| GC40054 | CCT241161 | 1163719-91-2 | MAPK Signaling | ||
A multi-kinase inhibitor | |||||
| GC40547 | RK-20448 | 479501-40-1 | Tyrosine Kinase | ||
A multi-kinase inhibitor | |||||
| GC41114 | Necrostatin-5 | 337349-54-9 | Signaling Pathways | ||
A RIP1 kinase inhibitor | |||||
| GC50045 | PD 166285 dihydrochloride | 212391-63-4 | Apoptosis | ||
A tyrosine kinase inhibitor | |||||
| GC52516 | Erbstatin | 100827-28-9 | DNA Damage/DNA Repair | ||
A tyrosine kinase inhibitor | |||||
| GC19547 | LOXO-292 | 2152628-33-4 | Tyrosine Kinase | ||
A RET kinase inhibitor | |||||
| GC45054 | Tie2 Inhibitor 7 | 1020412-97-8 | Signaling Pathways | ||
Blocks Tie2 kinase activity | |||||